Quercetin is a flavonoid polyphenol abundant in apples, grapes, onions, tea, tomatoes, and capers. In addition to incorporating quercetin-rich foods in the diet, quercetin can also be taken as an effective supplement for moderating allergic responses and respiratory concerns.

In fact, quercetin’s ability to inhibit mast cell release has been shown to be superior to that of cromolyn sodium, a drug commonly used for the prevention and treatment of allergies and asthma.

How Quercetin Works:

• Inhibits mast cell and eosiniophilic activation (which trigger allergic symptoms)
• Reduces histamine release
• Relaxes the trachea
• Reduces inflammatory compounds in cells that line the inside of the lungs
• Balances the production of IgE production in the lymph nodes
• Balances the response of T-helper cells (Th-1 and Th2) and decreases inflammatory cytokine activity

When Quercetin is Indicated:

• Seasonal allergies
• Acute respiratory infections
• Chronic obstructive pulmonary disease (COPD)
• Asthma
• Autoimmune conditions

Synergy with Vitamin C:

We all know vitamin C supports the immune system. A randombized, double-blind clinical study found that a combination of quercetin and vitamin C was more effective in reducing CRP and IL-6 (inflammatory markers) than either nutrient used alone. Vitamin C makes quercetin more bioavailable.

I like this Aller-C supplement, which provides both quercetin and vitamin C.

Boswellia- Another Herb for Inflammation and Allergies:

I often recommend boswellia for joint pain and inflammation, but it can also be used to address allergies and asthma. Boswellia modulates the 5-LOX pathway, which is associated with allergies, asthma, and respiratory inflammation.

I recommend patients ideally start these supplements (along with a probiotic and a healthy diet rich in COLOR) prior to allergy season. They can be taken throughout the season to help minimize symptoms.

Resources:

Quercetin with the potential effect on allergic diseases

Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans

Immunomodulatory activity of boswellic acids of Boswellia serrata Roxb

Editor’s Note: The information in this article is intended for your educational use only. Always seek the advice of your physician or other qualified health practitioners with any questions you may have regarding a medical condition and before undertaking any diet, supplement, fitness, or other health program.